The renal clearance of hydrochlorothiazide in sufferers with typical renal operate is 285mL/min. Individuals by using a creatinine clearance of 31-80mL/min have a median hydroxychlorothiazide renal clearance of 75mL/min, and sufferers having a creatinine clearance of ≤30mL/min have an average hydroxychlorothiazide renal clearance of 17mL/min.One
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